Terry O. Matsunaga

Research Professor
Joint Faculty


Post-doctoral Fellow, National Institute for Drug Abuse, 1989

PhD, Pharmaceutical Chemistry, University of California San Francisco, 1987

Pharm.D, Clinical Pharmacy, University of California San Francisco, 1980

BS, Biochemistry, University of California Berkeley, 1975

Research Interests:

Microbubble and phase-change contrast agents for ultrasound imaging and therapy

Teaching Interests:

Drug and gene delivery, contrast agent development, Ultrasound imaging.


Terry Matsunaga came to the Deptartment of Medical Imaging in 2007 after 16 years in the private sector, where he was a primary developer of lipid-coated microbubbles that have been approved by the FDA and sold under the brand name Definity. In addition, Matsunaga focused his attention on the use of ultrasound-mediated bubble cavitation for dispersing of clots (Sonothrombolysis).

Currently, his efforts focus on targeted microbubbles for cancer imaging, point-of-view diagnostics, and drug and gene delivery. His most recent efforts revolve around phase-change contrast agents for tumor detection and extravascular applications.

Since 2010, he has chaired the steering committee for Science Moving Towards Research Translation and Therapy, or NHLBI SMARTT. Matsunaga is a member of the Cancer Imaging Program of the University of Arizona Cancer Center and is a member of the Acoustical Society of America.

University of Arizona College of Engineering
Department of Biomedical Engineering 1127 E James E. Rogers Way P.O. Box 210020 Tucson, AZ 85721-0020